A huge blast rocked a mass demonstration in the Afghan capital, Kabul leaving at least 61 people killed and 207 injured.
The attack was claimed by terrorist group Islamic State.
The numbers were confirmed to Afghan TOLOnews network and Pajhwok agency, as well as to Reuters.
Graphic television footage from the site of the blasts showed many dead bodies lying on the bloodied road.
Security officials have arrived at the scene of the blast and the injured have been taken to nearby hospitals.
Shortly after the attack, Taliban spokesman Zabihullah Mujahid denied the group was behind the bombing, saying it “did not have any involvement or hand in this tragic attack.”
Emergency vehicles were at the site and wounded were being carried away.
Much of the city centre had been sealed off with stacks of shipping containers as the march began earlier on Saturday.
Security was tight with helicopters patrolling overhead.
The blasts came some three weeks after a suicide bomber attack that killed dozens of people.
"Opportunist terrorists went among the protestors, set off explosions that killed and wounded a number of our countrymen including security and defense personnel," President Ashraf Ghani said in a statement.
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